The primary scientific interest of our team is to understand how gene expression is regulated during development. We particularly focus on the role of 3D genomic organization in this regulation. By challenging prevailing paradigms - largely based on vertebrate genome research - we aim to bring forward a more nuanced understanding of how animals use 3D genome organization to regulate gene expression. We combine this scientific goal with the development of experimental and bioinformatics spatial OMICs tools (within the frame of the Spatial-Cell-ID EquipEx project) applied to our scientific questions. Until recently, we have used Drosophila melanogaster embryogenesis as a model system, but have recently incorporated a non-conventional model, the planktonic chordate Oikopleura dioica, due to the unique structure of its genome.

07/2025: Our work is featured by the CNRS!

Actualité CNRS Biologie

07/2025: Congratulations to Claire for obtaining an FRM PhD fellowship!

09/2024: We are recruiting!!
2 open positions in our lab: 1 postdoctoral fellow and 1 research assistant
See Join Us

07/2024: We are recruiting a postdoctoral researcher! See JOIN US

07/2022: Deevitha obtained an FRM doctoral fellowship!

09/2021: Many new(ish) comers this fall! Margarita and Baptiste are back as PhD student after doing their M2 internship in the lab. Deevitha is joining us "in situ" for her M2 internship after doing her M1 internship from home in India. Welcome back! :)

05/2021: Baptiste obtained a IADoc@UdL PhD fellowship to stay in our team as a graduate student in the fall. Congrats!!!

03/2021: We welcome Damien, our new lab manager!

02/2021: We welcome Margarita and Baptiste, our new Master2 students!

01/2021: We are recruiting a technical assistant / lab manager. More info here.

12/2020: The EquipEx+ "Spatial-Cell-ID" project, to buy equipement and develop spatial transcriptomics projects has been funded!

12/2018: We obtained a "Projet Emergent" grant from the ENS for a collaborative project with Cédric Vaillant

08/2018: We are hiring a postdoctoral fellow. More info.

09/2017  The lab is now funded by the ERC Starting grant!

07/2017   The lab is now funded by the ATIP-Avenir program!

12/2016   We are hiring! Come join this new adventure :)  More info.